Home » Chronic fatigue syndrome is a physiological (and not psychosomatic) condition

Chronic fatigue syndrome is a physiological (and not psychosomatic) condition

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Chronic fatigue syndrome is a physiological (and not psychosomatic) condition

Scientists have made a breakthrough in understanding chronic fatigue syndrome, a debilitating condition that affects millions of people worldwide. A recent study published in Nature Communications reveals the physiological basis of the disease, shedding light on the immune system, brain activity, and cardiorespiratory functions underlying the symptoms.

The study, conducted on a small sample of 17 individuals recovering from infections that triggered chronic fatigue syndrome, found several key abnormalities. Functional MRI tests showed reduced brain activity in the temporoparietal junction, a region responsible for coordinating motor actions. This abnormal brain activity could explain the debilitating fatigue experienced by patients, leading to difficulties in motor control and a sense of exhaustion.

Furthermore, patients with chronic fatigue syndrome exhibited higher heart rates and delayed blood pressure recovery after physical exertion. The immune system also showed signs of abnormal activation, with alterations in T cells and imbalances in intestinal bacteria diversity. These findings suggest a possible connection between immune system activation, autonomic nervous system dysfunction, and brain chemistry alterations in chronic fatigue syndrome.

Lead researcher Avindra Nath emphasized the importance of understanding these interconnected processes to develop effective treatments for chronic fatigue syndrome and related conditions like long covid. The study provides valuable insights into the biological mechanisms underlying the symptoms of chronic fatigue syndrome, challenging the misconception that the condition is purely psychosomatic.

Moving forward, researchers aim to validate these findings in larger patient populations and explore potential therapeutic strategies targeting the immune-brain-organ axis implicated in chronic fatigue syndrome. By uncovering the complex interplay of immune, neural, and physiological factors contributing to the condition, scientists hope to pave the way for improved diagnosis and management of chronic fatigue syndrome in the future.

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