Covid: study, cured more protected against variants with a single Pfizer dose

Rome, May 3 (beraking latest news Health) – People cured of coronavirus are better protected, even from variants, with a single dose of the Pfizer vaccine. This is the conclusion of a study published by the journal Science and reported by Roberto Burioni’s Facebook page, Medical Facts.

To understand whether single-dose vaccination, with or without prior infection, could also confer protective immunity to variants, the researchers analyzed T and B cell responses after the first dose of Pfizer / BioNTech mRNA vaccine. in healthcare workers, with or without previous infection with Wuhan-Hu-1 Sars-CoV-2, which is the type of Chinese coronavirus that triggered the pandemic. “After the first dose, the study explains, individuals with a previous native virus infection showed increased T cell immunity, memory B cell antibody response to the virus spike and neutralizing antibodies effective against B.1.1.7 (the English variant) and B.1.351 (the South African variant) “.

“Healthcare professionals – we read on MedicalFacts – who received a dose of vaccine without previous infection showed instead a reduced immunity. The English and South African mutations induced abrogated or unchanged T cell responses on these individuals depending on the polymorphisms of the Human leukocyte antigen. Vaccination with a single dose of the Pfizer vaccine of those who have already been infected, therefore finds Science, substantially improves the neutralizing antibody responses against the variants, while those who have not had Covid have a low protection against the variants if the received dose is only one “.