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Covid vaccine, the adverse effects of the third dose comparable to those of the second

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The first study on the adverse effects of the third dose of mRNA vaccine, then Pfizer or Moderna, comes from the United States, a country where the third dose has already been injected into fragile and immunosuppressed patients since August. The study – by the CDC, the Centers for Disease Control and Prevention, an important American organization – reassures those who had feared an increase in side effects. And it does so precisely on the eve of an enlargement of the audience of people to whom it will be administered.

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The study ran from mid-August to mid-September and the CDC analyzed the adverse effects reported by 12,600 people who took the third dose and took part in a voluntary monitoring system. Here are some numbers: reactions in the injection area, such as pain and redness, were reported by 79.4% at the third dose, compared to 77.6% at the second dose; systemic reactions such as fever and headache in slight decrease, to 74.1% after the third dose (and to 76.5% after the second).

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“Most of the local and systemic reactions were mild to moderate, all temporary and in most cases within the day after vaccination,” said the authors of the study that analyzed those who received the third dose of the vaccine received. originally, Pfizer or Moderna. And this is because the numbers of those who had received an additional dose of Johnson & Johnson or a dose of a different vaccine than the first two doses (heterologous vaccination) were numerically insignificant.

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These results confirm those obtained from a small third-dose study conducted by Pfizer scientists, which had substantially confirmed comparable adverse effects after the second and third doses. Meanwhile, after the CDC study concluded, about 2.2 million Americans have received the third dose since September 19.

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