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Fasting yes or no against cancer? What does the doctor say

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Fasting yes or no against cancer?  What does the doctor say

New Study Shows Caloric Restriction May Impact Cancer Treatment

A new study coordinated by the National Cancer Institute of Milan, called Breakfast 2, is set to explore the effects of caloric restriction on patients with triple-negative breast cancer who are candidates for pre-surgical chemo-immunotherapy. The study aims to compare the effects of caloric restriction with a healthy but not restrictive diet on cancer patients.

The interest in caloric restriction as a way to improve health has been growing over the years, with many studies highlighting the potential benefits of reducing daily calorie intake. Epidemiologist Franco Berrino, who has been studying the role of nutrition in human health for years, explains that caloric restriction can help reduce inflammation and blood sugar levels, which are important factors in cancer development.

Studies have shown that reducing food intake by 20-25% can significantly reduce the risk of heart disease, cancer, and diabetes. Berrino suggests that people trust the scientific evidence and eat a little less, avoiding “junk” foods and opting for natural foods instead.

When it comes to fasting, different dietary patterns can be followed, including the ‘fasting-mimicking’ diet, caloric restriction, and intermittent fasting. These approaches have been linked to improved health outcomes and reduced risk factors for diseases.

Experts advise that special eating strategies should be approached with caution and with expert support. As a general rule, reducing daily calorie intake, especially in the evening, can be a good lifestyle habit to adopt.

The Breakfast 2 study will provide valuable insights into the impact of caloric restriction on cancer treatment and outcomes, shedding light on the potential benefits of dietary interventions for cancer patients.

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1 comment

Federico Bozzetti May 3, 2024 - 11:02 am

It is intriguing that NCI in Milan launches a program of calorie restriction during chemotherapy while an RCT by Senft et al (J Clin Oncol 41:5285-5295) just showed that a normal diet and exercise were associated with a higher pathological response rate in patients with hormone receptor–positive/human epidermal growth factor receptor 2–negative and triple-negative breast
cancer undergoing neoadjuvant chemotherapy.


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