Home » Few people know but this very common drug protects against colorectal cancer

Few people know but this very common drug protects against colorectal cancer

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Cancer is one of the leading causes of death in our country. Science has made many steps forward, but there is still no definitive cure. Of course, prevention comes first. It is essential to regularly do all the necessary screenings according to the age groups. Here, for example, are the exams and checks that all women should undergo from the age of 30.

It is also good to eat well and eat certain foods often. To prevent some cancers, it is helpful to eat these fruits and vegetables more often. Meanwhile, the scientists continue their research, and in recent years they have focused on aspirin and its hypothetical cancer prevention role.

Acetylsalicylic acid, this is the exact term, is a common non-steroidal anti-inflammatory drug (NSAID) used in case of flu, headache, fever, toothache, rheumatic, muscle and pre-menstrual pain. Aspirin is also administered to subjects with cardiovascular diseases.

A recent analysis showed that regular intake of aspirin in a “cardiological dose”, ie equal to 75-100 mg per day, for 10 consecutive years, in a healthy man of about 55 years of age prevents death in 2 subjects out of 100 for antitumor effect.

Few people know but this very common drug protects against colorectal cancer

All over the world various experiments are being carried out in this sense. In Italy, the Aida study (Adiuvant Intervention with Daily Aspirin) refers to the specific case of colorectal cancer and the risk of metastasis following surgery.

To circulate freely in the patient’s body and avoid attack by the immune system, cancer cells “coat” themselves with platelets. It seems that acetylsalicylic acid prevents platelets from gathering around cancer cells circulating in the body.

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Lynch syndrome

The CAPP2 study, published in the Lancet journal, was carried out on subjects with Lynch syndrome (which increases the risk of cancer, including colorectal cancer). This study showed a reduction in the risk of getting this type of cancer in as many as 63% of subjects who took aspirin. In spite of those who instead took placebo.

Further confirmation can be found in an article published by Harvard researchers in the journal JAMA Oncology. Healthy subjects without any predisposition to cancer, if they take aspirin for 6 consecutive years, see a 19% reduction in the risk of developing colorectal cancer.

With resolution 607, on June 26, 2018, Aifa (Italian Medicines Agency) agreed to have information about its possible protective effect against colorectal cancer included in the package leaflet of aspirin. Few people know but this very common drug protects against colorectal cancer

However, according to the US Preventive Services Task Force (USPSTF) document, preventive therapy based on acetylsalicylic acid has limitations.

It is recommended for adults aged 50-59 with a life expectancy of at least 10 years, a risk of cardiovascular disease equal to or greater than 10% and not at risk of bleeding.

It is not recommended to take aspirin as a preventive measure for colorectal cancer in the remaining age groups, as the results are less convincing.

(We remind you to carefully read the warnings regarding this article, which can be consulted who”)

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