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in excess it can cause a heart attack

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in excess it can cause a heart attack

New Study Shows Excessive Vitamin B3 Intake Linked to Cardiovascular Risk

A new study from the Cleveland Clinic in the United States has revealed that taking too much vitamin B3, also known as niacin, can increase the risk of cardiovascular disease, including heart attack and stroke. The research, published in Nature Medicine, identified the molecular mechanism by which an overdose of niacin can be harmful.

Niacin is a water-soluble vitamin that is essential for cell respiration, nervous system functioning, blood circulation, and digestion. It is naturally found in foods like white meat, spinach, peanuts, beef liver, and certain types of fish. However, it is also commonly used in supplements to boost the immune system, fight aging, and lower cholesterol and triglyceride levels.

The study found that excessive niacin intake can lead to the production of metabolites that promote inflammation in blood vessels, increasing the risk of cardiovascular disease. The researchers analyzed blood samples from over 4,000 people and found that higher levels of a niacin metabolite called 4PY were associated with an increased risk of cardiovascular disease, independent of other known risk factors.

The research sheds light on the potential dangers of overdosing on niacin supplements and highlights the importance of consulting with a doctor before taking any over-the-counter supplements. The study’s senior author, Stanley Hazen, emphasized the importance of focusing on a balanced diet rich in fruits and vegetables, rather than relying on supplements for nutritional needs.

While niacin has been traditionally used to lower cholesterol levels, the study suggests that its effects on cardiovascular health may be more complex than previously thought. The findings underscore the need for further research to better understand the impact of niacin on cardiovascular disease and develop interventions to reduce inflammation and protect against heart disease and stroke.

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