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Microplastics also in the arteries, proven damage to the heart. « Medicine in the Library

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Microplastics also in the arteries, proven damage to the heart.  « Medicine in the Library

Microplastics also in the arteries, proven damage to the heart.

Posted by giorgiobertin on March 7, 2024

Microplastics and nanoplastics (MNPs) are emerging as a potential risk factor for cardiovascular disease in preclinical studies.

The extensive study by researchers from the University of Campania Luigi Vanvitelli is published in ‘New England Journal of Medicineproves how atherosclerotic plaques often contain micro and nanoplastics based on polyethylene (Pe, detected in 58.4% of cases) or polyvinyl chloride (or PVC, identified in 12.5% ​​of cases), two of the most widely consumed plastic compounds around the world, used to make products ranging from containers to coatings, from plasticized films to building materials.

The pro-inflammatory effect could be one of the reasons why micro- and nanoplastics lead to greater instability of the plaques and therefore a greater risk of them breaking, giving rise to thrombi and thus causing heart attacks or strokes.” – explains Dr. Raffaele Marfella, first author.

Data collected in vitro and in experimental animals have already shown that micro- and nanoplastics can promote oxidative stress and inflammation in the cells of the endothelium that lines the blood vessels, but also that they can alter the heart rhythm and contribute to the development of fibrosis and abnormalities of heart function: these results show for the first time in humans a correlation between the presence of micro- and nanoplastics and a greater cardiovascular risk.

Read abstract of the article:
Microplastics and Nanoplastics in Atheromas and Cardiovascular Events
R. Marfella and Others
N Engl J Med 2024; 390:900-910 DOI: 10.1056/NEJMoa2309822

This entry was posted on marzo 7, 2024 a 6:51 am and is filed under News-research. Tagged: cardiology, prevention, public health, toxicology. You can follow any responses to this entry through the RSS 2.0 feed.

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