Home » neurologists ask to be able to use the drug cladribine for multiple cycles

neurologists ask to be able to use the drug cladribine for multiple cycles

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neurologists ask to be able to use the drug cladribine for multiple cycles

Effectiveness on the reduction of inflammatory activity, but also on the progression of long-term disability, without surprises from a safety point of view. A therapy that is taken orally for a limited period of time. These are the characteristics of cladribinaeffective drug for the treatment of relapsing multiple sclerosisthe most common form of this disease.

“We have verified that the therapy is effective in reducing inflammatory activity, but also in the progression of long-term disability” he confirms Francesco Patti, Head of the Multiple Sclerosis Center at the G. Rodolico San Marco Polyclinic in Catania. «Another important aspect concerns the quality of life: the patient, on oral treatment and with a few tablets for a limited period of time, can almost forget that he is sick».

Multiple sclerosis: neurologists ask to be able to use the drug cladribine for multiple cycles

Treatment with cladribine involves taking the drug for two cycles, one at the beginning of the first year and another at the beginning of the second year, while in years 3 and 4 no treatment with the drug is required. However, current guidelines do not allow a third cycle with cladribinebut according to Italian and European neurologists a third cycle could bring benefits from an efficacy point of view for a long period of time.

«The Italian Society of Neurology is expressing its opinion on this aspect as we are increasingly moving towards personalized treatment», he explains Claudio GasperiniDirector of the Neuroscience Unit at the Company
San Camillo-Forlanini hospital in Rome. «Data are emerging from studies also conducted in other countries that demonstrate how cladribine, also used with a third cycle, can benefit patients. We therefore hope that, in the context of personalized therapy, there will be the possibility for us neurologists to be able to use the drug even beyond two years.”

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