You smokeyou suffer from high pressure e you are married? Coverage of the vaccine it lasts less. The survey comes from a new study carried out byLa Sapienza university and from Umberto I Polyclinic from Roma, which identified demographic, clinical and social factors that interfere with the immune response following Covid-19 vaccination. The findings were published in the Journal of Personalized Medicine and, in fact, pave the way for customizable vaccination programs.
There are those who receive greater, longer-lasting coverage from the anti-Covid vaccine, and those who do not. Depends on what? From the state of health and lifestyle: in fact, there are several variables that can affect the ability of individuals to acquire this immunity.
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Research
The study saw the participation of health workers from the university hospital: a sample of 2065 health workers from the Policlinico Umberto I, who had been administered the anti Covid-19 vaccine with Pfizer BioNTech mRna, was in fact subjected to two samples. of blood. The first after 1 month and the second after 5 months from the second vaccination. “All those involved – explains Stefania Basili, coordinator of the study – were given a questionnaire to collect personal information and a quantitative serological test was performed to detect antibodies to protein S (Spike) of the Sars-CoV2 virus. , the best tool for assessing acquired immunity following vaccination or infection “.
“Dramatic” drop in antibody levels
The results showed that one month after vaccination, subjects with a previous Covid-19 infection and younger ones have higher levels of antibodies than the other people in the sample considered. In contrast, autoimmune diseases, chronic lung diseases, and smoking are related to lower levels of antibody responses. Five months after vaccination, a median decrease of 72% in the antibody level was observed, but this is less evident in women and in subjects with a previous infection. On the other hand, in smokers, hypertensive people and the less young, a dramatic drop of about 82% in anti-Spike antibody levels was found.
Rector Polimeni: “Lifestyle also counts against covid”
Among the authors of the research also the director of Sapienza Antonella Polimeni, who declares “the study highlights how the pursuit of health, even in the face of pandemic situations, underlies a more general principle of social well-being. In fact, lifestyle factors play an important role in the immune response. The first cure is therefore the raising of the health culture and the quality of life standards ».
Antibodies ok for singles, less so in married people
The researchers also revealed greater retention of antibody responses in single or cohabiting subjects than in married, divorced or widowed subjects, although this association could be due to other unexplored clinical variables, such as eating habits and body mass index.
“Although our study has confirmed many already known correlations, it has also taken into consideration for the first time – concludes the coordinator Stefania Basili – many factors including the level of education, the type of work, marital status and the load of involvement. familiar. Beyond the results, the hope is that our analysis will encourage further research to investigate the effects of variables linked to gender and lifestyle on the immune response, bringing out a personalized and precision medicine “.
He goes to the emergency room and tests positive for Covid: he takes gasoline and sets a fire https://t.co/9tuG15K19g
– I read (@leggoit) July 7, 2022
Last updated: Friday 8 July 2022, 16:34
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