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what is Alessandro Baricco’s disease and how is it treated

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What is chronic myelomonocytic leukemia that Alessandro Baricco suffers from?

“The Lmmc is the most frequent of myelodysplastic-myeloproliferative syndromes – reports the AIL website (Italian Association against leukemia, lymphomas and myelomas – and is a disease characterized by the increase of a specific population of white blood cells: monocytes”.

In other words, “chronic myeloid leukemia is a tumor caused by the uncontrolled multiplication of a type of bone marrow cell called a stem cell. The tumor transformation of the stem cell is due to an acquired genetic alteration, called the Philadelphia chromosome, which is characteristic of the disease – we also read on the website of the Hematological Clinic of Pavia – Chronic myeloid leukemia accounts for about 15% of leukemia cases e it is estimated that it affects around 1,150 people every year in Italy, males more often than females. The estimated incidence rate is 1-2 cases per year per 100,000 people. The median age at diagnosis is about 65 and only about 30% of patients are under the age of 60 at diagnosis. “

How to cure

The allogeneic transplant (by a donor, almost always a close family member, ed) of stem cells is the only treatment with curative potential, but in many cases – given the high age of the majority of patients – it is difficult to implement. . However, it is recommended in high-risk cases.

In high-risk cases not eligible for transplantation, azacitidine and, in proliferative cases, hydroxyurea can be used to check the white blood cell count.

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In case of anemia, erythropoietin can be used in low-risk patients.

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