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Puglia also has its “patient zero” for monkeypox, the monkeypox. “When he learned it was smallpox, the world fell on him,” she says Mauro Grandolfo62, the dermatologist of the Polyclinic who on Wednesday 8 June had the intuition that those rashes on the body of a 36-year-old resident in the province of Bari, the first, tested positive for monkeypox, were not rashes like the others.