Original title: New crown vaccine booster significantly increases the duration of the immune response of rhesus monkeys. Source: Qianlong.com
International war “epidemic” operation
Science and Technology Daily, Beijing, October 24th (Reporter Liu Xia) American scientists wrote in the latest issue of “Science” that their research on macaques showed that injecting new crown vaccine booster shots can enhance the neutralizing antibody in macaques. Concentration, and produced a high level of protection. The latest research results support an increase in the vaccination rate of the booster vaccine for the elderly, people with existing health conditions, and high-risk exposure groups.
Scientists from the National Institutes of Health, Johns Hopkins University and other institutions said that about 6 months after the macaque was vaccinated with the first dose of the new vaccine, they were injected with the mRNA-1273 new crown vaccine booster. The body was targeted at all known vaccines. The concentration of neutralizing antibodies of the mutant strain of the new coronavirus will increase significantly. Moreover, the enhanced neutralizing antibody response lasted for at least 8 weeks, and the intensity was significantly higher than the intensity of the antibody response generated by the previous vaccination, resulting in a high level of protection, which means that the booster injection can significantly limit the new coronavirus in rhesus monkeys. Reproduction in the lungs and nose.
These data indicate that the booster needle will trigger a strong immune memory response, and may extend the duration of immunity.
The researchers also determined that the mRNA-1273 vaccine developed against the original new coronavirus and the vaccine against the beta mutant strain of the new coronavirus are equivalent in enhancing the antibody response and providing protection.
This study began 6 months ago, when the beta mutant strain was a global epidemic strain, so the researchers focused on this strain. Related research claims that beta mutant strains can show the greatest anti-neutralization ability by reducing the effectiveness of the vaccine. The researchers said that the new research is mainly aimed at beta mutant strains that have strong resistance to neutralizing antibodies, and the new scheme enhances the immune response on this basis, and is more suitable for delta mutant strains that have weak resistance to neutralizing antibodies. .
They said that in humans, a dose of mRNA-1273 booster injection is expected to extend the protection period and effectiveness for respiratory infections caused by the epidemic new coronavirus strain.
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