Home » Zhong Nanshan: In response to the “Delta” strain, the previous concept of “close contacts” has to be changed-IT & Health

Zhong Nanshan: In response to the “Delta” strain, the previous concept of “close contacts” has to be changed-IT & Health

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How to judge the current local epidemic situation in Guangdong? What good experiences does Guangdong have in dealing with the first community transmission of Delta mutant strains in China? Regarding vaccination, should the vaccination work for minors and the elderly be accelerated? On June 25, the headquarter reporters had a dialogue with Academician Zhong Nanshan and made the latest research and judgment on the new crown pneumonia epidemic.

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In order to reduce the risk of the spread of the epidemic, Guangdong has adopted the most stringent control measures to prevent the spread of the epidemic

Academician Zhong Nanshan, academician of the Chinese Academy of Engineering and director of the National Respiratory Diseases Clinical Medicine Research Center, said that in response to the epidemic, Guangzhou has responded to the epidemic in China by quickly identifying the source of infection, accurately identifying the transmission chain, and updating the concept of “tight connection”. In the first phase of the “epidemic” of the Delta variant virus community infection, phased results have been achieved.

Zhong Nanshan, academician of the Chinese Academy of Engineering and director of the National Respiratory Diseases Clinical Medicine Research Center:

First, the source of infection was quickly identified, and the chain of transmission was quickly identified in Guangzhou. On May 21, because the provinces, autonomous regions, and municipalities also received reports, the source of infection was identified that afternoon. Subsequent high-quality epidemiological investigations, the epidemiological investigations were very timely. There were almost 150 patients, all of whom were genetically tested. This was not done in other places. After almost every genetic test, it was found that it was a grandmother ( After passing), it is clear, and the transmission chain is very clear. It enables us to understand the whole ins and outs of the disease, its development trend, and how to control it, and provides us with a very clear data support.

second,Corresponding to the Delta strain, we used to talk about close contacts, this concept has to be changedBecause of the high load of the Delta strain, the exhaled gas is highly toxic and highly infectious. In the past, what is called a close contact? Two days before the onset of illness, the family members of the patient, the family members have the same office, or have meals, meetings, etc. within one meter. This is called close contact.But now the concept of closet has to change,In the same space, in the same unit, in the same building, in the same building, four days before the onset of illness, the people who got along with these patients were close contactsIt is precisely because of the change in this concept that a number of different management modes, such as sealing, banning and banning, etc., will be adopted. Therefore, the change of this concept is to control our key crowds. Guangdong is very strict, as far as possible to prevent spillovers outside the province, so in order to reduce the risk of spread of the epidemic caused by the movement of people, especially to prevent the spread to other places in the province, and the outgoing province, May 31, the time of the onset, 6 On the 2nd of the month, the prevention and control headquarters in Guangzhou, Foshan, etc. all issued notifications, requesting that the green code of the health code should be used when leaving Guangdong, Guangzhou, and the Buddha, and there is a 72-hour nucleic acid test negative certificate; by June 7th, the number will be increased. , Further shorten the nucleic acid negative certificate that takes 48 hours to leave Guangzhou and Foshan. So until June 24, we have not spread it outside the province.

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Entry personnel do not need to increase the isolation time during the isolation period, and the frequency of nucleic acid testing should be increased

Regarding the current concerns about whether the incubation period of the Delta variant virus is longer and whether immigrants should increase the quarantine time and strengthen the quarantine management, Academician Zhong Nanshan also said that it is not necessary.

Zhong Nanshan, Academician of the Chinese Academy of Engineering, Director of the National Respiratory Diseases Clinical Medicine Research Center:

I don’t think it needs to be increased. Because in general, most of the incubation period is not long, and a very small number of incubation periods are long. If you increase the isolation observation, it will do more harm than good. We should strengthen the nucleic acid testing of these personnel during the isolation period and strengthen the frequency testing. I think this is an effective method.

Guangzhou will build 5,000 independent space international health stations

In response to the next epidemic prevention and control, Academician Zhong Nanshan said that for the possible re-emergence of Delta variant virus infection,Because of its high intensity of infection,Fever clinics in hospitals should strengthen control measures, and isolation places should be more standardized.

Zhong Nanshan, Academician of the Chinese Academy of Engineering, Director of the National Respiratory Diseases Clinical Medicine Research Center:

Due to the very high infection intensity of the Delta variant virus, strict control measures should be adopted in fever clinics in hospitals. There are not too many hospitals in most cities across the country that really meet the specifications of fever clinics: independent buildings, 20 meters away from other buildings… (Fever clinics) must have strict control, good physical isolation, and relatively independent , There are completely different entrances and exits from ordinary outpatient clinics, so you have to choose the position of the downwind direction and so on.

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Although some high-risk areas in Guangzhou have adopted the entire area to be isolated in hotels, this has solved many problems, but ordinary hotels are not qualified as isolated hotels. Probably more than 80% of the country’s tourists, and even close to 90% of foreign tourists are here.Guangzhou has decided to build a Guangzhou International Health Station covering an area of ​​250,000 square meters in the suburbs. There are 5,000 independent spaces. The rooms are strictly isolated (standards) and will not be infected with each other. , This is called an isolated hotel.

At present, the commonly used domestic vaccines are still effective against delta mutant strains, everyone should fight

Academician Zhong Nanshan also pointed out:“At present, the commonly used domestic vaccines are still effective against the delta mutant strain, and everyone should fight it.”

Minors and the elderly should speed up vaccination

Academician Zhong Nanshan said in an interview about the current epidemic: In the spread of the delta mutant strain, the main and severe patients are mostly elderly people, but there are also children. Therefore, these two groups of people should be vaccinated.

The following is the interview record

Reporter: After this round of epidemic situation, do you think that in groups such as minors and the elderly, should the vaccination be accelerated?

Zhong Nanshan, academician of the Chinese Academy of Engineering and director of the National Respiratory Diseases Clinical Medicine Research Center:

The elderly should be particularly strengthened, because a lot of previous studies were done abroad, and a lot of research abroad was done for speed, and the elderly have made little progress. This information is not enough to support the safety of our elderly vaccinations. Therefore, the elderly were not mentioned in the indications at that time. However, as more and more vaccinations were made later, hundreds of thousands of them have been vaccinated, and they all proved to be very safe, so the elderly need to vaccinate more. This time, the delta strain is mainly used for severely ill patients. They are elderly people and also have children. So I think the priority vaccination should be given to the two groups of people, and the booster vaccination should also be done.

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Reporter: At present, with the three vaccines on the market, do you have any suggestions for minors and the elderly in the selection of vaccination?

Zhong Nanshan, academician of the Chinese Academy of Engineering and director of the National Respiratory Diseases Clinical Medicine Research Center:

It is impossible to make an absolute head-to-head comparison, so an absolute conclusion cannot be drawn. But now it seems that if more than 90% of all vaccines are used in China, the biggest advantage is that it is safer and has few side effects;

Secondly, it has a definite protective effect, especially after checking the delta strain. From the laboratory data and from more than 160 limited data in Guangzhou, it is found that the close contacts have been vaccinated, and the vaccination has been completed. There is no vaccine for the whole process,Its protective effect can be seen, it has a protective effect, with more than 60% protection against infections, and close to 80% protection against severe illnesses.

Therefore, this should be considered safe to inoculate a vaccine with inactivated whole virus. As for others, such as subunit protein vaccines and adenovirus vaccines, it will take some time to accumulate more information before we can have a clear view.

Reporter: After we have finished the vaccine, if it is said that the antibody drops or the antibody is not so strong after half a year or after a certain period of time, does it prove that the vaccine has failed?

Zhong Nanshan, academician of the Chinese Academy of Engineering and director of the National Respiratory Diseases Clinical Medicine Research Center:

It is difficult to draw conclusions at present. Antibody is just one of the indicators, proving that it serves as humoral immunity. There are generally two types of immune functions, one is called humoral immunity, the other is called cellular immunity, and of course some are called memory immunity and so on. Well, since it is only a part of humoral immunity, if the titer of the antibody drops, it does not completely mean that its protective function has disappeared. Therefore, it is not enough to use antibodies as the only indicator. We are now discussing the functional indicators including humoral immunity, cellular immunity, cellular memory, etc., to illustrate the protective effect of a certain vaccine.

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