The criteria of the confirmed case I am: patient of age 10 or younger presenting with acute hepatitis (with negative test to the viruses of hepatitis A, B, C, D, E) with the value of specific enzymes, “aspartate aminotransferase (AstST) or alanine aminotransferase (ALT), greater than 500 U / L”. Also significant to date according to which to discriminate the cases, that is starting “January 1, 2022”