“THE AZD1222 AstraZeneca VACCINE is associated with the development of thrombotic disorders which clinically resemble heparin-induced thrombopenia, treatable if identified immediately, but which show a different serological profile. “This is the conclusion of the research conducted between Germany, Canada and Austra, by the German regulatory agency for drugs Paul Ehrlich institut, from German University of Greifswald, Canadian University McMaster and the University of Vienna It must be said immediately that the study is still in its initial phase and it is therefore too early to draw conclusions and create alarmism on the subject.
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The result is published on the Research Square website, which houses studies that have not yet passed review by the scientific community. The research was conducted on nine patients in Germany and Austria, including 8 women, with an average age of 36, with thrombosis episodes 4-16 days after vaccination. Seven patients had cerebral thrombosis, one pulmonary embolism, and one splanchnic vein thrombosis. Four patients died. None of them had received heparin prior to the onset of symptoms. The authors propose, on the basis of the finding of a high titer of anti-platelet factor 4 (PF4) antibodies in severe cases, a mechanism similar to that of heparin-induced thrombocytopenia (HIT), which would also explain the latency between vaccination and thrombosis. . The subject is so delicate that the editor precedes the pre-print with a note reiterating that WHO still supports the use of the AstraZeneca vaccine.
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