In the final two years, the University Hospital of Ferrara has made out there to sufferers, in its Hemodynamics Laboratory, an progressive and non-invasive intervention for Treatment of drug-resistant hypertension: renal denervation. Before this surgical procedure there was no various to drug therapy.
Globally, in line with a latest evaluation by the World Health Organization, there are over 1.28 billion individuals affected by hypertension and roughly half don’t understand they’ve it and don’t obtain any therapy, with critical dangers for cardiovascular well being. According to the Italian Society of Arterial Hypertension – Italian League Against Arterial Hypertension, within the Emilia Romagna Region 41% of males and 30% of girls are hypertensive. Recent information additionally exhibits that, once more within the area, greater than half (56%) of individuals over 64 endure from arterial hypertension, equal to 574 thousand individuals in the entire of Emilia – Romagna.
In some instances, hypertension proof against pharmacological therapy could happen if the blood strain worth is especially excessive (above 140/90 mmHg) regardless of the remedy. We then speak about Resistant Arterial Hypertension: a very harmful power illness as it’s related to a rise in cardiovascular danger, together with stroke and coronary heart assault, in addition to coronary heart failure and nephropathy. In different instances, nevertheless, hypertension just isn’t managed both as a result of the affected person doesn’t tolerate a number of medicine because of negative effects of some energetic elements, or as a result of the affected person is poorly compliant with drug remedy, particularly when taking a number of tablets is required .
In all these instances, an progressive and secure choice is the renal denervation process.
“Before this process there have been no therapies apart from pharmacological ones. – says Professor Gabriele Guardigli (within the picture), Director of Cardiology on the University Hospital of Ferrara – Today, with this system, after roughly 3-6 months, in not less than 85-90% of sufferers we’re in a position to receive an enough discount in blood strain values, consequently decreasing the identified cardiovascular, cerebrovascular and nephrovascular issues secondary to the hypertension itself”.
The renal denervation operation carried out within the haemodynamic laboratory of the Arcispedale Sant’Anna is reserved for sufferers affected by resistant arterial hypertension and consists of a minimally invasive process which impacts the renal nerve ganglia chargeable for the hyperstimulation of the renal arteries and the resultant hypertension. After sedation and a small incision, the surgeon inserts a really skinny catheter that enables him to function on the ganglia. Through the spiral-shaped machine, radiofrequency (RF) power is delivered, thermo-ablating the renal plexuses organized across the arteries and sustaining the performance of the organ unchanged.
After the operation the catheter is eliminated with out leaving any kind of implant. “The discount of blood strain is especially necessary in sufferers on polytherapy, – concludes Professor Guardigli – as a result of it improves the prevention of issues secondary to hypertension similar to myocardial infarction, cerebral stroke and cerebral hemorrhage”.