May is the month in which we celebrate World Systemic Lupus Erythematosus Day (or SLE or lupus), a potentially life-threatening autoimmune disease. The cause that triggers the disease is not known. The symptoms, which vary greatly from person to person, include fever, joint and muscle pain, tiredness, skin rashes, mouth ulcers, alopecia, neuro-psychiatric disorders, which can last several weeks. The target organs are primarily represented by skin, joints, and kidneys.
An estimated 5 million people have lupus worldwide. 90% are women who present the first symptoms of the disease between the ages of 15 and 45, with persistence for their entire life. In Italy, the prevalence is 40-50 cases per 100,000 inhabitants.
There is currently no therapy that can lead to recovery, but early diagnosis and some therapies that act on the symptoms and mechanisms of the disease can allow control. In Italy, the diagnostic delay is approximately 20 months, attributable to the complexity of the symptoms, a lack of knowledge about the disease on the part of doctors and the population, and the limited presence of specialist clinical structures. It is indicated for patients a non-pharmacological approach in addition to drugs, with interventions on lifestyle and disease education to improve quality of life and adherence to therapy.
As we commemorate World Systemic Lupus Erythematosus Day, it is important to raise awareness about this disease and support those who are living with it. Let us work towards better understanding, early diagnosis, and effective management of lupus to improve the lives of those affected by this condition. © All rights reserved.