Ovarian cancer: what the HRD test is and why it is useful for choosing therapy

Ovarian cancer is characterized by significant genetic deficits that alter the mechanisms for repairing DNA damage. “The HRD test capable of detecting when the mechanism of homologous recombination or Homologus Recombination Deficiency does not work has existed for some years,” he continues. Sandro Pignata, director of the Medical Oncology Division, Department of Uro-Gynaecology – National Cancer Institute Irccs Fondazione G. Pascale, Naples. It is a ‘correction system’ which, if it stops working, causes the DNA to generate new errors. These are, in fact, the main biological characteristics of ovarian cancer.”

Subjects