Over 900 chemicals exhibit characteristics that cause breast cancer.
Posted by giorgiobertin on January 12, 2024
And new study improves understanding of how endocrine-disrupting chemicals affect breast cancer risk.
The researchers of Silent Spring, developed a rapid way to predict whether a chemical might cause breast cancer, based on the characteristics of the substance itself. This study provides regulators and manufacturers with guidance to quickly identify potentially harmful chemicals and find safer alternatives.
Researchers identified a total of 921 chemicals that could promote the development of breast cancer. 90% of chemicals are those to which people are commonly exposed in consumer products, foods and beverages, pesticides, medications and workplaces.
More than half of the chemicals cause cells to produce more estrogen or progesterone, known risk factors for breast cancer, and about a third activate the estrogen receptor. “Breast cancer is a hormonal disease, so the fact that so many chemicals can alter estrogen and progesterone is concerning“, says Professor Kay.
The study’s authors hope their list of chemicals can inform the U.S. Environmental Protection Agency’s (EPA) plan and better protect the public from harmful exposures.
Read abstract of the article:
Application of the Key Characteristics framework to identify potential breast carcinogens using publicly available in vivo, in vitro, and in silico data.
Kay, J.E., J.G. Brody, M. Schwarzman, R.A. Rudel.
Environmental Health Perspectives Volume 132, Issue 1 CID: 017002 10 January 2024
Source: Silent Spring Institute, Newton, Massachusetts, USA
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