Dall’India it was considered “a variant of interest”. It is the delta plus, a mutation of the Delta variant, that once called Indian. Thus the Covid does not stop changing from what was discovered in China at the end of 2019. And the variants become more and more predominant. If before it was the English one, now called “alpha”, to be the most widespread in most of Europe, now it is the delta that spreads quickly. And therefore there is growing concern that it may become the new enemy to fight against.
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Delta plus variant, when it was identified
The Delta Plus was first spotted in India in April. While it was reported in a bulletin of Public Health England, the British government agency, on 11 June. It is a subtype of the Delta variant, which has acquired a mutation – called K417N – of the coronavirus spike protein present in the beta variant.
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Where is it
Public Health England, the British government agency, found 40 cases of the new Covid sequence. But cases of positives to the new variant have not only been found in England alone. Even in the United States 83 positives were reported for the delta plus variant last Friday. But there are also in Canada, India, Japan, Nepal, Poland, Portugal, Russia, Switzerland and Turkey.
Symptoms, what causes
Increased transmissibility, easier binding to lung cells and potential reduction in monoclonal antibody response, which could reduce the effectiveness of a life-saving monoclonal antibody therapy administered to some hospitalized Covid patients. These are the three aspects that worry most about the plus variant. Although as regards the monoclonals it must be noted that it is an experimental treatment and few people have been found to be suitable.
How to cure
There are three drugs approved and used to date to treat Covid. Remdesivir, dexamethasone (with a favorable opinion from the European Medicines Agency) and enoxaparin. It is therefore these that can also be used against the Delta plus variant, at least for symptomatic cases. As for monoclonal antibody therapy, as noted earlier it may not work with this coronavirus mutation.
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