The psoriasis, an immune-mediated dermatological condition that affects approximately 125 million people worldwide, not only involves obvious skin lesions but can also lead to cardiovascular health risks. One studio published on the Journal of Investigative Dermatology has in fact highlighted an increased risk of cardiovascular events in people suffering from psoriasis, regardless of traditional cardiovascular risk factors such as smoking, age, diabetes and hypertension.
Psoriasis, the role of inflammation
The inflammation associated with psoriasis has been identified as a critical factor which contributes to development of cardiovascular diseases. This inflammatory process can promote plaque formation in blood vessels, leading to atherosclerosis, a risk factor for heart disease. However, the precise mechanisms of this interaction are not yet fully understood and require further investigation.
I study
And recent study explored the relationship between psoriasis and CMD, focusing on the tiny blood vessels that supply the heart muscle. This study found that people with psoriasis are more likely to have reduced coronary flow reserve, indicative of CMD. The duration and severity of psoriasis were found to be related to a higher incidence of CMD, suggesting a direct link between the severity of the skin condition and cardiovascular risk.
Early identification of psoriasis and timely therapeutic intervention can play a crucial role in reduce the cardiovascular risks associated with the disease. Effective treatment of psoriasis could help improve coronary microvascular function and prevent future cardiovascular events. Furthermore, therapeutic approaches targeting systemic inflammation may be considered to reduce cardiovascular risk in people with psoriasis.
Further research is needed to fully understand the underlying mechanisms and to develop therapeutic strategies aimed at reducing cardiovascular risk in people with psoriasis. However, early identification of the condition and timely treatment may offer significant opportunities to improve the cardiovascular health of this population.