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In Tokyo, the Nikkei index, which includes 225 stocks, fell by 0.6 percent to 38,189.54 points, while the broader Topix was 0.6 percent lower at 2,725.70 points. In terms of individual stocks, there were some clear winners and losers based on business figures and stock-specific news: Chip supplier Lasertec jumped 16.1 percent after the results published after the trading session on Tuesday exceeded estimates. West Japan Railway rose 7.7 percent after the company said it would buy back 4.1 percent of its shares. The biggest loser was JGC Holdings with a loss of 11.2 percent after a disappointing sales forecast.