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It all started in 1897 in the pharmaceutical laboratory in Elberfeld. At that time, Bayer’s headquarters were still in Wuppertal, not Leverkusen. According to a laboratory report from October 10th, the young chemist Felix Hoffmann succeeded in converting the fever-reducing and pain-relieving salicylic acid in such a way that it does not cause nausea. Acetylsalicylic acid, ASA for short, is the name of Hoffmann’s discovery.