Recent research conducted by Russian scientists has highlighted the possibility of synthesizing some compounds capable of curbing neurodegenerative processes. By activating intracellular mechanisms to counteract the deterioration of brain cells, the compounds would directly attack amyloid plaques, extracellular formations that cause Alzheimer’s. This perspective could become applicable to a whole range of neurodegenerative diseases according to scholars. Alzheimer’s and Parkinson’s can be slowed down with this new technique according to science and below we see what it consists of.
How could the brain be protected from deterioration
Those who want to keep their brains young and healthy know how important it is to fight neurodegenerative diseases. In a previous article we showed what connections exist between brain health and diet for example: “Few people know that to keep the brain healthy it is important to cure this organ”. A little momentum certainly cannot be lacking in maintaining optimal health. A practical example is the one in the article “How to stay young at 60 with a very simple but very effective exercise”.
In the study published in the European Journal of Medicinal Chemistry, scientists have devised some low-toxic chemical compounds that can trigger a protective reaction on neuronal tissue. In essence, the compounds that the researchers synthesized would perform a protective function of the cells by counteracting cellular stress. These compounds, in fact, would contribute to synthesize specific proteins defined as “heat shock” that counteract neurodegenerative diseases. In this way we would intervene to stem the proteotoxic stress that plays a key role in many of the diseases that attack the nervous system. Alzheimer’s and Parkinson’s can be slowed down with this new technique according to science and the study’s data could open up new application frontiers.
A possible new era for clinical interventions
The proteotoxicity that occurs in the presence of neurodegenerative diseases consists in an accumulation of damaged proteins inside the cell. By increasing the synthesis of heat shock proteins through specific compounds, neurodegeneration would be counteracted. Scientists have currently tested the compounds on tissues from rats that had injuries following head trauma. The results showed an increase in the survival of neurons with good outcomes for therapeutic purposes. The next step will be to test the new compounds in preclinical trials. New hope therefore opens up for research and also for early intervention on patients.
Deepening
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