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The first three children subjected to fresh CAR-T cell therapy in Italy were successfully treated, thanks to an innovative automated production. The three young patients had a particular type of leukemia – B-cell precursor acute lymphoid leukemia (ALL-BCP) – which was refractory to all conventional therapies.
The three children were treated with genetically modified cells produced at the Pharmaceutical Workshop of the Bambino Gesù Pediatric Hospital (OPBG) in Rome through an automated system, developed as part of the CAR-T Italia project.
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