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The clinical case that testifies to the rapidity and frequency of SARS-CoV 2 infection exists, and was presented during the European Congress of Clinical Microbiology and Infectious Diseases held in Lisbon on April 26th. This is the case of a 31-year-old who was struck by the virus twice 20 days apart. The vaccinated woman was first targeted by the Delta variant and then by Omicron.