The nanoparticle skin patch monitors tumor size.
Posted by giorgiobertin on February 4, 2024
Medical researchers and chemical engineers at National Tsing Hua University in Taiwan have developed a new wearable patch that can provide continuous monitoring of tumors under the skin.
The patch, made of a thermoplastic polyurethane (TPU) film embedded with hafnium oxide (HfO 2 ) nanoparticles, can also transmit real-time data to a smartphone to support monitoring of tumor growth and regression.
A skin patch, along with two carbon tape electrodes, was placed on the mice’s skin over the site of a small subcutaneous tumor. The skin patch was able to effectively track tumor growth under the skin before treatment, with its impedance measurements steadily increasing as the tumor grew. Once the tumor volume reached a predefined critical limit, it sent an alert to the researcher’s smartphone that treatment needed to begin. The patch was also able to detect impediment in tumor growth once anti-tumor treatments began.
The TPU-HfO 2 DE voltage sensor [dielettrico elastomerico] developed wearable demonstrates exceptional precision in measurements, maintaining accuracy even when dealing with minimal tumor volumes.
The use of the patch to monitor tumor size in mouse models of cancer is reported in the journal “ACS Nano“.
Read the full text of the article:
Harnessing HfO2 nanoparticles for wearable tumor monitoring and sonodynamic therapy in advancing cancer care.
Siboro PY, Sharma AK, Lai PJ, et al.
ACS Nano 2024, 18, 3, 2485–2499 Publication Date:January 10, 2024
This entry was posted on febbraio 4, 2024 a 6:30 am and is filed under News-ricerca, Tecno Sanità.
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