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«The risk-benefit ratio was correct during the pandemic, but that vaccine is now outdated»

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«The risk-benefit ratio was correct during the pandemic, but that vaccine is now outdated»

«Who has been vaccinated with AstraZeneca you don’t have to worry: the very rare cases of adverse reactions are immediate, not diluted over time. «If anything, long Covid may have an impact. And in any case when that vaccine was used the relationship between risks and benefits was certainly favourable.” The professor Guido Rasi, full professor of Microbiology at Tor Vergata, was consultant to General Figliuolo in the vaccination campaign; in the last decade he was executive director of the EMA (European Medicines Agency) and even before that general director of AIFA (Italian Medicines Agency).

How can we explain the withdrawal of the AstraZeneca anti-Covid vaccine?
«It has been surpassed by other vaccines with superior safety and efficacy profiles. It has a widely known margin of side effects such that the risk-benefit ratio remains valid throughout age only in the presence of a high intensity of infection.”

When the pandemic is at its peak it makes sense to accept that very low percentage of risk.
“Exact. And that’s not the case at this stage. Let’s be clear: as long as it was used, with a very high intensity of the pandemic, the risk-benefit ratio was favorable. Again: It hasn’t been updated for variants. So the virus now bypasses his protection. And today we also have drugs to treat Covid.”

Has mRNA technology won?
«However, it will need to be updated. For viruses that mutate rapidly, today it is the best, for flexibility and speed of production.”

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