From selective immunosuppressants, to antineoplastic agents passing through different categories of inhibitors including those of TNF-alpha, interleukins, calcineurin and other immunosuppressants.
Multiple sclerosis and Covid vaccine, some drugs reduce antibodies
Aifa has published the list of the main drugs with immunosuppressive activity to be considered for the purpose of selecting the subjects for which the additional dose of the anti Covid-19 vaccine may be indicated.
Third dose vaccine, because it is better to wait before giving it to everyone
by Antonio Cassone * and Roberto Cauda **
The list is not exhaustive, but only indicative of the main drugs whose intake, simultaneously or possibly in the six months prior to the administration of the previous doses of the vaccine, may have reduced the antibody response.
Covid, third injection but not for everyone. And halved dosage
by Antonio Cassone * and Roberto Cauda **
According to AIFA, the published list must be used as part of a clinical evaluation that takes into account not only the drugs used, but also the specific diagnosis, clinical history and current status of the individual patient.
Finally, it is reiterated that “the decision to administer an additional dose of vaccine must be made in relation to the clinical characteristics of the patient, not based on the dosage of anti-spike antibodies as a reference standard is not currently available and no reference standard has been defined a concentration considered optimal / adequate “.
Covid, even the frail can be super-protected
by Donatella Zorzetto
As regards the timing of the administration of the third dose for patients under treatment, “the type of medicine used for the treatment of specific underlying diseases must be taken into account in order to guarantee the best possibility of response to the vaccine and in any case not it may occur earlier than 28 days after the second vaccine dose “.
Covid, third dose but low dose: half or a quarter of the normal one
by Giuseppe del Bello
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