According to the National Health Commission, as of April 7, 2022, 31 provinces (autonomous regions and municipalities) and the Xinjiang Production and Construction Corps have cumulatively reported vaccination against the new coronavirus3.289463 billion doses.As of April 5, 1,243.226 million people had completed the full course of vaccination.In fact, as early as mid-February, with the approval of the Joint Prevention and Control Mechanism of the State Council, the National Health and Health Commission has begun to deploy sequential booster immunizations.
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The so-called sequential booster immunization refers to the use of vaccines with different technical routes from basic immunization for booster immunization.
For those who have completed the whole process of vaccination with Sinopharm Zhongsheng Beijing, Beijing Kexing, and Sinopharm Zhongsheng Wuhan inactivated vaccine, they can choose the recombinant protein vaccine of Zhifeilong Kema or the adenovirus vector vaccine of CanSino for sequential booster immunization.
According to the latest report of the “Health Times”, on April 8, Zhong Nanshan, an academician of the Chinese Academy of Engineering, mentioned in the online live class “Scientific Guidance to Fight the Epidemic and Climb the Medical Peak” held online for Nankai University,According to my country’s “dynamic clearing” strategy, it is recommended to use xenogeneic vaccines as sequential vaccination, and “strengthening immunity is imperative”.
During the course, Academician Zhong Nanshan shared real-world data on heterologous vaccination in Brazil.
Through the observation of more than 14.36 million subjects, it was found that 14 to 30 days after two injections of Kexing vaccine, the effective rate of preventing infection was 55%, and 34.7% after 180 days; 82.1% after 14-30 days, 180 Diva was 72.5%.
The data show that the third injection (booster injection) can effectively improve the protective efficacy, but the effectiveness of the third injection of the same vaccine is not significantly improved.On the contrary, the third injection of xenogeneic vaccine can greatly improve the prevention rate of infection.
Specifically,Two doses of Kexing vaccine and boosted immunity with mRNA vaccine can prevent infection rate up to 92.7% after 14-30 days, and prevent severe disease up to 97.3%.
Academician Zhong Nanshan pointed out that through the analysis of the immunogenicity of the vaccine in the laboratory, we can observe the production of antibodies and the ability of cellular immunity. Live high.
Zhong Nanshan revealed,The third shot he took himself was Zhifei’s recombinant protein new crown vaccine.
Zhong Nanshan proposed,According to my country’s dynamic clearing strategy, it is not only to reduce the severe rate and mortality, but also to reduce the process of infectivity. To achieve the goal, the use of heterogeneous vaccines is used as sequential vaccination.