According to Israeli doctors, the opportunity should be considered of assigning only one administration to those who have already had the infection, considering it as a reminder. This would allow, among other things, to have immediately new availability of doses for those who need it most
by Agnese Codignola
According to Israeli doctors, the opportunity should be considered of assigning only one administration to those who have already had the infection, considering it as a reminder. This would allow, among other things, to have immediately new availability of doses for those who need it most
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As the vaccination campaigns go on, the first, important data on the efficacy and safety of vaccines authorized in so-called real life situations begin to be disclosed, that is, obtained from immunized people with the most diverse and non-different characteristics, as happens in studies. clinical, relatively homogeneous and in good health.
One of the most anticipated indications still comes from Israel, the country with the highest number of vaccinated in relation to the population, and concerns a category of people about which there is much discussion: those who have already been infected with Sars-CoV 2 and are then cured. .
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Should we vaccinate them? There are many questions, given that the national programs do not provide for their exclusion, for now. The question is relevant, because according to the data available today, natural immunity lasts – in the vast majority of cases – not less than 6-8 months, and the vaccine would therefore be relatively useless.
Furthermore, not subjecting these people to vaccination or, at least, putting them at the bottom of the priorities, would mean having immediately available several million doses of the vaccine (in the world). Not to mention that, until now, there was no data on the effects of vaccination on the immune system of people who already have specific active immunity.
But now doctors at Safed’s Ziv Medical Center have analyzed the immune response of 514 medical staff who received the first dose of Pfizer’s vaccine between December and January, identifying 17 who had been infected in a period ranging from one to ten. months before. And, as they write in Eurosurveillance, they saw that, in the latter, the production of antibodies is of an order of magnitude greater than that seen in the others (the average concentration of IgG is 68.6 units per milliliter, but in the healed it reaches 573.3), with no substantial differences between ethnic groups or ages.