Comirnaty 10 mcg / dose is administered, after dilution, intramuscularly (preferably in the deltoid region of the arm) as a cycle of 2 doses (of 0.2 mL each) 3 weeks (21 days) apart. . But in children undergoing solid organ transplantation, haematopoietic stem cell transplantation or with marked impairment of the immune response due to disease-related causes or pharmacological treatments, it is possible to administer an additional dose at least 28 days after the second dose. This is what is clarified in the circular of the Ministry of Health on the “extension of indication of use of the Comirnaty vaccine (BioNTech / Pfizer) for the age group 5-11 years”.
The circular after the green light from Ema and Aifa
A circular that comes after the green light, last December 1, by the technical scientific commission of AIFA – which in turn accepted the opinion expressed by the European Medicines Agency (EMA) – to the extension of indication of use of the Comirnaty vaccine (BioNTech / Pfizer), in the specific formulation of 10 mcg / dose, for the age group 5-11 years.
The document reports the AIFA opinion in which it is noted that “although the SARS-CoV-2 infection is certainly more benign in children, in some cases it can be associated with serious consequences, such as the risk of developing the inflammatory syndrome multisystem, which may also require hospitalization in intensive care “.