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Covid vaccine: protected from the first dose

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Getting vaccinated is not just about protecting yourself, but also protecting others. And now we have the proof too: mRna vaccines, such as those produced by Pfizer-BioNTech e Modern, prevent disease and are also able to block the transmission of the virus. Two recently published studies shed light on the debated question of the possible contagiousness of vaccinated people. The first study, carried out by Centers for Disease Prevention and Control (CDC), has shown that mRNA vaccines prevent the development of symptoms and even contagion.

The other study, conducted by the Technion – Israel Institute of Technology e del Maccabi Healthcare Services (Mhs), and published in the journal Nature Medicine, shows that those who have received even the first dose of the vaccine, if infected, have such a low viral load that they are unlikely to infect other people.

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“Two good news comes from these two studies: the confirmation of the effectiveness of these vaccines in preventing the onset of infections Covid-19 serious and the demonstration that those who are vaccinated also protect others from contagion ”, comments the former EMA number one Guido Rasi, scientific director of Consulcesi who, next Tuesday, will participate in the web conference “Covid-19: between vaccines and variants”, Together with the president of Consulcesi Massimo Tortorella. “The message is clear: don’t hesitate to get vaccinated. Doing so – he underlines – means protecting oneself and others ”.

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It study conducted by the American CDC it involved about 4 thousand health workers and workers belonging to essential categories, that is, the categories vaccinated with priority. Each subject was tested weekly to verify the positivity or not. The monitoring lasted 13 weeks, precisely from mid-December 2020 until mid-March 2021, in a period in which the new “more contagious” variants were already circulating. Well, the results showed that people who had completed the vaccination course were 90 percent less likely to get infected. Even just 14 after the first dose, the effectiveness of the vaccination was around 80 percent.

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It Israeli studyInstead, it focused on a set of data on vaccinated subjects who are members of the Maccabi Healthcare Services (MHS), which were already over a million on 11 February. The researchers performed tests to track down any infections between December 21, 2020 and February 11, 2021. In all, the data of just under 5 thousand subjects were analyzed.

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Analysis of the viral load of the infected vaccinates showed that it decreased significantly 12 days after inoculation of the first dose of the vaccine. Therefore, as early as 12 days after administration from the first dose, the first defenses of the immune shield begin to be activated, which become complete 7 days after the administration of the second dose. After comparing the viral loads detected in the vaccinated with those of the control group, composed of about 3 thousand unvaccinated and positive subjects SARS-CoV-2, the researchers concluded that the viral load in vaccine recipients is 2.8 to 4.5 times lower than in unvaccinated people.

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“In addition to the substantial protection of vaccinated subjects – explain the authors – vaccines anti-Covid they could reduce the viral load in infections (if they occur, ed) and thus further suppress subsequent transmission “. This means that the hope of reducing the contagion index, as the vaccinations proceed, is quite realistic. “It is now clear that the vaccine is capable of stopping the transmission of the virus,” he points out Rasi. “Vaccines therefore once again prove our best chance of getting out of this pandemic,” he concludes.

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