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Why, after being hit, does it tend to come back and then even manage to kill the organism it invaded? It is the question of questions evoked by multiple myeloma. The one they started from Annamaria Gullà and Eugenio Morellioncologists and researchers, thirty-seven-year-old wife and husband, and who never stop asking themselves, in their journey that began immediately after graduation and which, step by step, is continuing.