Home » my country’s local epidemic is still in the development stage, and relevant vaccine research and development has made positive progress | Vaccine | Epidemic | New Coronary Pneumonia_Sina News

my country’s local epidemic is still in the development stage, and relevant vaccine research and development has made positive progress | Vaccine | Epidemic | New Coronary Pneumonia_Sina News

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my country’s local epidemic is still in the development stage, and relevant vaccine research and development has made positive progress | Vaccine | Epidemic | New Coronary Pneumonia_Sina News

Source: Central Commission for Discipline Inspection and State Supervision Commission website

The Joint Prevention and Control Mechanism of the State Council held a press conference on March 19 with the theme of “Strictly, Practically, Scientifically and Accurately Grasp the Situation of Epidemic Prevention and Control”.

On March 19, the Joint Prevention and Control Mechanism of the State Council held a press conference on epidemic prevention and control and vaccination. Lei Zhenglong, deputy director and first-level inspector of the National Health Commission’s Bureau of Disease Control and Prevention, introduced that the current fourth wave of the new crown epidemic in the world is still running at a high level. From March 1 to 18, my country has reported more than 29,000 new crown pneumonia infections. For example, it affected 28 provinces. “Overall, the local epidemic situation in my country is still in the development stage, and many provinces are facing the prevention and control of the Omicron epidemic in many cities at the same time.”

Wu Zunyou, chief expert of epidemiology at the Chinese Center for Disease Control and Prevention, said that the current focus of prevention and control work lies in two aspects. The outbreak of the epidemic, especially in densely populated places such as schools, prisons, and nursing homes. The difficulty lies in how to detect all the infected people in time. In order to ensure “timely” and “all”, in the process of epidemiological investigation, on the one hand, big data is used to sort out the entire transmission chain to maximize the discovery of all possible infected persons in the transmission chain, and on the other hand, nucleic acid testing for all employees is carried out to make the best possible efforts. A round of testing may be completed within 1-3 days, and each round of testing must ensure that the screening of the entire population within the determined local area is completed. “If we can screen all staff in a timely manner, generally speaking, 3-4 rounds of nucleic acid screening can basically achieve zero cases at the social level.” Wu Zunyou said.

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Talking about the recently confirmed “Delta Chron” strain, Wu Zunyou said that from the current limited data, no significant changes have been observed in either epidemiology or clinical manifestations. However, due to the relatively short period of time when new strains were discovered and the relatively small number of cases, there is no way to draw conclusions in terms of pathogenicity, infectivity, and ability to escape from vaccines. It happens all the time, whether it is the mutant strain Delta, Omicron, or a new mutant strain, the prevention and control practices in the past two years or more have proved that our normalized prevention and control measures can effectively prevent and control the mutant strain. caused a massive epidemic.”

The press conference also introduced the development of vaccines against Omicron mutants. “In fact, our country’s vaccine research and development team has been in action since the beginning of the Omicron variant. So far, the development of monovalent and multivalent vaccines against Omicron variant has made positive progress. “Zheng Zhongwei, the leader of the vaccine research and development team of the scientific research team, said that in terms of inactivated vaccines, monovalent, delta + Omicron bivalent, prototype strain + delta + Omicron trivalent vaccines have been developed. In the research and development work, preclinical research has been basically completed, and production verification has been carried out; in terms of recombinant protein vaccines, the research and development of Alpha + Beta + Delta + Omicron quadrivalent vaccine has been carried out, and is applying for overseas clinical trials; Adenovirus vector Vaccines and mRNA vaccines are also actively promoting some preclinical research work.

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The recently released ninth edition of the diagnosis and treatment plan mentioned two newly approved antiviral drugs. Li Xingwang, chief expert of the Center for Diagnosis and Treatment of Infectious Diseases of Beijing Ditan Hospital, said when introducing the relevant situation, it can be seen from the results of the preliminary clinical research data. It has been found that patients with mild and ordinary patients who may become severe or even dead can use these two drugs within 5 days of onset, and their hospitalization rate and case fatality rate are significantly reduced. “Therefore, after these two drugs are included in the diagnosis and treatment plan, it will play a great role in improving the treatment rate and reducing the mortality rate.” Li Xingwang said.

In addition, regarding the issue of how to ensure the normal medical needs of the people in the areas where the epidemic occurs, which is of concern to the public, Jiao Yahui, director of the Medical Administration and Hospital Administration, said that it is necessary to focus on key groups such as patients who need regular treatment, acute and critically ill patients, as well as pregnant women and the elderly. , children and other special groups to ensure their medical needs.

“To get through the ‘last meter’ to see a doctor, we must solve the problem of ‘one out, one entry’ and ‘one come and one return’.” Jiao Yahui said, “one out and one entry” is to ensure the closure and control area and the people in the control area. Can get out of the door of the community and enter the door of the hospital. Medical institutions must strictly implement the first-diagnosis responsibility system and the emergency and critically ill rescue system. “One-on-one” is to solve the problem of transportation for ordinary people to see a doctor. If the resources can meet the demand, for critically ill patients, 120 ambulances can be used to transport them. For other regular treatments, the local government should coordinate the settlement, requisition or use volunteer vehicles, and transport them to and from the hospital for treatment.

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