He was treated for leukemia with a bone marrow transplant in 2019 and since then, in addition to being cured of the tumor, he is also in remission from HIV. Three years ago he also stopped taking anitretroviral therapy. The case of Paul Edmonds, who at 68 is the oldest patient to be in remission from HIV (there are 5 known cases in total), was illustrated in the New England Journal of Medicine.
His case “shows that it is possible to achieve HIV remission even at an advanced age and after living with HIV for many years,” said Jana K. Dickter, a doctor at the City of Hope National Medical Center Duarte, near of Los Angeles where the patient is being treated.
On February 6, 2019, the researchers reconstruct, Edmonds received a hematopoietic stem cell transplant for the treatment of acute myeloid leukemia. The cells, transplanted from a third-party donor, were characterized by a genetic mutation known as delta-32 on both copies of the CCR5 gene. This characteristic appears to make people resistant to HIV. The transplant was successful, despite some temporary complications.
Today Edmonds is the oldest patient to have achieved remission thanks to the transplant and also the one who had lived with HIV the longest before the procedure: 31 years.
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