Genetic defects are also more often inherited by young fathers

Previously, it was assumed that the older a man was, the more likely he was to develop a mutation that would lead to malformations. Linz researchers have now shown in the journal “Genome Biology and Evolution” that even young men can have potentially pathogenic mutations in their sperm. The scientists examined variants of the cancer-causing gene FGFR3. Among other things, we examined how the mutation frequency changes with age.