Home » Fem and University Cork (Ireland): the secret to reducing anxiety and stress? A targeted diet with psychobiotics – Lavis – Rotaliana

Fem and University Cork (Ireland): the secret to reducing anxiety and stress? A targeted diet with psychobiotics – Lavis – Rotaliana

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Fem and University Cork (Ireland): the secret to reducing anxiety and stress?  A targeted diet with psychobiotics – Lavis – Rotaliana

SAN MICHELE ALL’ADIGE. The Edmund Mach Foundation participated in the international study coordinated by University College Cork (Irlanda) which demonstrates how the virtuous combination of lifestyle and nutrition affects people’s mental health.

Focus of the study are psychobiotics, beneficial microorganisms that work alongside probiotics and which, by operating along the microbiota-intestine-brain axis, contribute to improving the performance of the human nervous system.

From this research, which in FEM involved the Metabolomics Unit of the Research and Innovation Center with the analysis of human biofluids, further confirmation of the benefits produced by these microorganisms arrives, taking a further step in the direction of a preventive or curative intervention through nutrition, syndromes such as depression, Alzheimer’s, autism or stress disorders in general.



In particular, 4 main elements of the diet that are able to improve mental health emerge from the research: omega-3 fatty acids, polyphenols, fibers and fermented foods. A balanced diet can be achieved, without having to take supplements, simply by associating large doses of fermented foods, such as sauerkraut, yogurt, kefir and kombucha, with a Mediterranean diet.

“With all the necessary limitations given by the duration of the survey and the small size of the study sample, it is possible to state that the adoption of a targeted diet can be a valid tool in reducing stress, anxiety and depression – he says Andrea Anesi, FEM researcher -. This research marks an important turning point and a starting point for further insights into the potential associated with the adoption of targeted diets for the treatment of mental disorders.

  • The combination of plant fibers and fermented foods develop psychobiotics
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The study did not consider single foods, but the articulated combination of fermented foods and vegetable fibres, in repeated administrations throughout the day and for a medium-long period (4 weeks). A real varied diet, therefore characterized by the presence of ingredients such as cabbage, leeks, onion and garlic, apples, bananas and small fruits, whole grains, legumes and fermented foods which favor the development of psychobiotic microorganisms in the intestine.

  • The study in FEM: human biofluids analyzed

The activity carried out by the Metabolomics Unit of the Research and Innovation Center concerned the analysis of human biofluids (plasma and urine) for the targeted quantification of the catabolites of essential amino acids and for the metabolites synthesized by the intestinal microbiota thanks to an innovative protocol developed in the last few years. By comparing two study samples, one characterized by the consumption of a diet with the characteristics highlighted above and the other by the consumption of a conventional diet, the people belonging to the first study group would have shown a reduction in stress at the end of the four weeks perceived compared to those who were part of the second group, associated with a standard diet.

  • Psychobiotic microorganisms and their benefits

In the intestine, psychobiotic microorganisms transform ingested food into a series of metabolites that have a positive effect on the brain, such as serotonin, the hormone of happiness. Any alterations in the functionality of the intestinal microbiota caused by stress or incorrect eating habits lead to a dysfunction in the intestinal-brain communication and therefore to the onset of stress or, in the most serious cases, of pathologies.

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